Principles of Human Physiology, Fourth Edition features integrated clinical coverage, challenging critical thinking questions, and a new flowchart visual style that makes it easier than ever for students to focus on key physiological processes. The new Fourth Edition now includes an even stronger focus on systems integration and clinical applications, an updated art program, and more in-chapter questions for developing critical thinking skills. In addition, features such as Chemistry Review boxes provide additional resources for students who need them, while Toolboxes and Discovery boxes allow instructors the option of delving into more detail about physiology topics.

Every new copy of the book comes packaged with the Interactive Physiology^®10-System Suite (IP-10) CD-ROM. The book also includes access to an expanded Physiology Place Companion Website, which includes new and updated resources from the Fourth Edition plus:

Table of Contents

1. Introduction to Physiology
2. The Cell: Structure and Function
3. Cell Metabolism
4. Cell Membrane Transport
5. Chemical Messengers
6. The Endocrine System: Endocrine Glands and Hormone Actions
7. Nerve Cells and Electrical Signaling
8. Synaptic Transmission and Neural Integration
9. The Nervous System: Central Nervous System
10. The Nervous System: Sensory Systems
11. The Nervous System: Autonomic and Motor Systems
12. Muscle Physiology
13. The Cardiovascular System: Cardiac Function
14. The Cardiovascular System: Blood Vessels, Blood Flow and Blood Pressure
15. The Cardiovascular System: Blood
16. The Respiratory System: Pulmonary Ventilation
17. The Respiratory System: Gas Exchange and Regulation of Breathing
18. The Urinary System: Renal Function
19. The Urinary System: Fluid and Electrolyte Balance
20. The Gastrointestinal System

21. Regulation of Energy Metabolism and Growth
22. The Reproductive System
23. The Immune System
24. Diabetes Mellitus: The Epidemic